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Blood Transfusion

New Findings in Blood Transfusion Described from American Red Cross

Published in Blood Weekly, January 27th, 2011

2011 JAN 27 -- New investigation results, 'Developing pathogen reduction technologies for RBC suspensions,' are detailed in a study published in Vox Sanguinis. "Numerous studies have evaluated a wide variety of photosensitizers and alkylating agents as candidates for a pathogen reduction process to be used in RBC suspensions. The methodologies that produce robust inactivation of pathogens with maintenance of RBC properties during storage involve those that specifically target nucleic acids," investigators in the United States report.

"This has been demonstrated through in vitro studies by flexible photosensitizers, which specifically target nucleic...

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