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Hematopoietic

Researchers at Eli Lilly and Company Release New Data on Hematopoietic

Published in Blood Weekly, February 24th, 2011

2011 FEB 24 -- Research findings, 'Hematopoietic proliferative lesions in the spleen of rasH2 transgenic mice treated with MNU,' are discussed in a new report. "In this study, rasH2-Tg mice treated with N-methyl-N-nitrosurea (MNU) developed exuberant hematoproliferative changes in the spleen that included dysplasia and features of neoplasia. Hematoproliferative change was characterized as exuberant proliferation of hematopoietic cells within the spleen that distorted but did not displace normal splenic morphologic features," investigators in the United States report.

"The hematopoietic cells were of mixed lineage, but one type, often erythroid,...

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