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Ischemia

Scientists at University of British Columbia, Department of Psychiatry Describe Research in Ischemia

Published in Blood Weekly, March 3rd, 2011

2011 MAR 3 -- Data detailed in 'Automated and quantitative image analysis of ischemic dendritic blebbing using in vivo 2-photon microscopy data' have been presented. "Ischemia induces a 'blebbing' of dendrites, a structural alteration where dendrites take on a 'beads on a string' appearance. We developed a toolkit program, BlebQuant, for quantitative automated bleb analysis to chart the morphology of dendrites labeled with GFP/YFP under normal conditions and after ischemia-induced damage," scientists in Vancouver, Canada report.

"In vivo 2-photon data from mouse layer 5 neurons with apical dendritic tufts extending to the cortical surface were examined...

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