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Angiogenesis

New Angiogenesis Research Reported from University of Pittsburgh

Published in Blood Weekly, June 16th, 2011

2011 JUN 16 -- According to a study from Pittsburgh, United States, "An externally regulated delivery model that permits temporal separation of multiple angiogenic factors was used for the delivery of basic fibroblast growth factor (bFGF) and platelet-derived growth factor (PDGF). While bFGF plays a significant role in the sprouting of new capillaries, PDGF plays a role in the recruitment of mural cells, which stabilize neovessels."

"However, these two factors have been shown to inhibit each other, when presented together. Using the externally regulated model, sequential delivery of bFGF and PDGF led to not only increased endothelial cell migration, but...

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