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Serine Endopeptidases

Reports from Queensland University of Technology Describe Recent Advances in Serine Endopeptidases

Published in Blood Weekly, July 28th, 2011

2011 JUL 28 -- According to the authors of recent research from Brisbane, Australia, "KLK15 over-expression is reported to be a significant predictor of reduced progression-free survival and overall survival in ovarian cancer. Our aim was to analyse the KLK15 gene for putative functional single nucleotide polymorphisms (SNPs) and assess the association of these and KLK15 HapMap tag SNPs with ovarian cancer survival."

"In silico analysis was performed to identify KLK15 regulatory elements and to classify potentially functional SNPs in these regions. After SNP validation and identification by DNA sequencing of ovarian cancer cell lines and aggressive ovarian...

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