Solid Cancer

Research Results from J. Nowak and Co-Authors Update Knowledge of Solid Cancer

Published in Blood Weekly, September 1st, 2011

2011 SEP 1 -- According to the authors of a study from Poznan, Poland, "NBN gene is considered as one of the low-to-moderate cancer susceptibility gene. At least 4 germline NBN mutations have been found in several malignancies in adults."

"In our studies, we observed the high incidence of germline mutation I171V of NBN gene in breast, colorectal, larynx cancer, and in multiple primary tumors. In this study, we would like to answer the question whether I171V germline mutation of NBN gene may constitute risk factor for solid tumors in children. The frequency of this mutation has been analyzed in patients with neuroblastoma (n = 66), Wilms tumor (n = 54),...

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Source: Blood Weekly (2011-09-01)

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