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Ischemia

Research from Affiliated Hospital in Ischemia Provides New Insights

Published in Blood Weekly, October 13th, 2011

2011 OCT 13 -- "Cerebral ischemia is one of the diseases that most compromise the human species. Therapeutic recovery of blood-brain barrier (BBB) disruption represents a novel promising approach to reduce brain injury after stroke," scientists in Shandong, People's Republic of China report.

"To determine the effects of calcitonin gene-related peptide (CGRP) on the BBB participate in stroke progression, rat cerebral ischemia reperfusion injury was induced by a 2-hour left transient middle cerebral artery occlusion (MCAO) using an intraluminal filament, followed by 46 h of reperfusion. CGRP (1 mu g/ml) at the dose of 3 mu g/kg (i.p.) was administered at the...

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