Dengue Fever

New Dengue Fever Research Has Been Reported by Scientists at University of Texas

Published in Blood Weekly, October 20th, 2011

2011 OCT 20 -- According to the authors of recent research published in the Journal of Biological Chemistry, "Fundamental aspects of interactions of the Dengue virus type 3 full-length polymerase with the single-stranded and double-stranded RNA and DNA have been quantitatively addressed. The polymerase exists as a monomer with an elongated shape in solution."

"In the absence of magnesium, the total site size of the polymerase-ssRNA complex is 26 +/- 2 nucleotides. In the presence of Mg2+, the site size increases to 29 +/- 2 nucleotides, indicating that magnesium affects the enzyme global conformation. The enzyme shows a preference for the...

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Source: Blood Weekly (2011-10-20)

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