Structural Biology

Research in the Area of Structural Biology Reported from Pennsylvania State University

Published in Blood Weekly, October 27th, 2011

2011 OCT 27 -- "Proteins are the molecules cells primarily rely on for catalysis, recognition, signaling, defense, locomotion, and structural integrity. Engineering proteins for improved function or new applications is a fast-growing segment of biotechnology and biomedicine," scientists writing in the journal Current Opinion in Structural Biology report.

"Experimental efforts based on the screening of large mutant libraries have led to many successes but they do not provide quantitative design principles and/or insight into the structural features that underpin the desired function. The computational de nova design of proteins promises to bridge this...

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Source: Blood Weekly (2011-10-27)

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