Thrombocytopenia
New Research on Thrombocytopenia from Duke University Medical Center Summarized
Published in Blood Weekly, October 27th, 2011
2011 OCT 27 -- Investigators publish new data in the report "Validation of the high-dose heparin confirmatory step for the diagnosis of heparin-induced thrombocytopenia." According to the authors of a study from Durham, North Carolina, "The diagnosis of heparin-induced thrombocytopenia (HIT) requires detection of antibodies to the heparin/platelet factor 4 (PF4) complexes via enzyme-linked immunosorbent assay. Addition of excess heparin to the sample decreases the optical density by 50% or more and confirms the presence of these antibodies."
"One hundred fifteen patients with anti-heparin/PF4 antibodies detected by enzyme-linked immunosorbent assay were...
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Source: Blood Weekly (2011-10-27)
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