Blood Research

Researchers at University of Sao Paulo Have Published New Data on Blood Research

Published in Blood Weekly, November 3rd, 2011

2011 NOV 3 -- "Mercury (Hg) exposure is associated with disease conditions, including cardiovascular problems. Although the mechanisms implicated in these complications have not been precisely defined yet, matrix metalloproteinases (MMPs) may be involved," scientists in Ribeirao Preto, Brazil report.

"The gene encoding MMP-2 presents genetic polymorphisms which affect the expression and activity level of this enzyme. A common polymorphism of MMP-2 gene is the C-1306T (rs 243865), which is known to disrupt a Sp1-type promoter site (CCACC box), thus leading to lower promoter activity associated with the T allele. This study aimed at examining how this...

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Source: Blood Weekly (2011-11-03)

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