Arthritis

Studies from Nagasaki University Reveal New Findings on Arthritis

Published in Blood Weekly, November 3rd, 2011

2011 NOV 3 -- According to the authors of recent research from Nagasaki, Japan, "Patients with systemic sclerosis (SSc) exhibit enhanced production of free radicals due to ischemia and reperfusion injury following Raynaud's phenomenon, an initial clinical manifestation. Oxidative stress induces cytokine production, inflammatory cell recruitment, and tissue injury in several inflammatory diseases."

"The aim of this study was to examine the effect of edaravone, a free radical scavenger, on the development of fibrosis and autoimmunity in two different mouse models of SSc. The bleomycin-induced SSc model in mice and the tight skin mouse model were used to...

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Source: Blood Weekly (2011-11-03)

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