Biochemistry
New Biochemistry Research from E.R. Werner and Colleagues Discussed
Published in Blood Weekly, November 3rd, 2011
2011 NOV 3 -- According to the authors of a study from Zurich, Switzerland, "BH4 (6R-L-erythro-5,6,7,8-tetrahydrobiopterin) is an essential cofactor of a set of enzymes that are of central metabolic importance, including four aromatic amino acid hydroxylases, alkylglycerol mono-oxygenase and three NOS (NO synthase) isoenzymes. Consequently, BH4 is present in probably every cell or tissue of higher organisms and plays a key role in a number of biological processes and pathological states associated with monoamine neurotransmitter formation, cardiovascular and endothelial dysfunction, the immune response and pain sensitivity."
"BH4 is formed de novo from GTP...
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Source: Blood Weekly (2011-11-03)
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