Infectious Diseases
Studies Conducted at University of Pennsylvania on Infectious Diseases Recently Published
Published in Blood Weekly, November 17th, 2011
2011 NOV 17 -- According to the authors of recent research from Philadelphia, Pennsylvania, "The virion protein 40 (VP40) and nucleoprotein (NP) of Ebola (EBOV) and Marburg viruses (MARV) play key roles during virion assembly and egress. The ability to detect interactions between VP40-VP40, VP40-NP, and NP-NP and follow these complexes as they traffic through mammalian cells would enhance our understanding of the molecular events leading to filovirus assembly and budding, and provide new insights into filovirus replication and pathogenesis."
"Here, we successfully employed a bimolecular complementation (BiMC) approach to visualize interactions between EBOV...
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Source: Blood Weekly (2011-11-17)
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