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Steatosis

Investigators at Mayo Clinic Target Steatosis

Published in Blood Weekly, November 24th, 2011

2011 NOV 24 -- According to the authors of a study from Jacksonville, Florida, "Progressive familial intrahepatic cholestasis (PFIC) results in liver cirrhosis. Therefore, some PFIC patients require liver transplantation (LT)."

"Although three types of PFIC have been identified, their etiologies include unknown mechanisms. A total of 717 recipients who underwent living-donor LT (LDLT) at < 20 yr old were enrolled in this study. Among these recipients, 14 PFIC recipients comprising 11 PFIC type 1 (PFIC1) and three PFIC type 2 (PFIC2) were evaluated. Three of 11 PFIC1 recipients died, while all three PFIC2 recipients survived. Eight of 11 PFIC1 recipients...

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