Protein Precursors
Researchers at University of Zurich Publish New Data on Protein Precursors
Published in Blood Weekly, December 22nd, 2011
2011 DEC 22 -- According to the authors of recent research published in the Journal of Biological Chemistry, "The acute-phase response is an inflammatory process triggered mainly by the cytokine IL-6. Signaling of IL-6 is transduced by activation of STAT3 (signal transducer and activator of transcription 3), which rapidly induces the production of acute-phase proteins such as haptoglobin and fibrinogen."
"Another target of the IL-6/STAT3 signal transduction pathway is the microRNA cluster miR-17/92. Here, we investigated the interplay of miR-17/92 and STAT3 signaling and its impact on the acute-phase response in primary human hepatocytes and hepatoma...
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Source: Blood Weekly (2011-12-22)
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