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Sepsis

Research in the Area of Sepsis Reported from University of Chicago

Published in Blood Weekly, January 5th, 2012

2012 JAN 5 -- Research findings, "Agent-based dynamic knowledge representation of Pseudomonas aeruginosa virulence activation in the stressed gut: Towards characterizing host-pathogen interactions in gut-derived sepsis," are discussed in a new report. "There is a growing realization that alterations in host-pathogen interactions (HPI) can generate disease phenotypes without pathogen invasion. The gut represents a prime region where such HPI can arise and manifest," scientists in Chicago, Illinois report.

"Under normal conditions intestinal microbial communities maintain a stable, mutually beneficial ecosystem. However, host stress can lead to changes in...

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