Pulmonary Fibrosis

Researchers from School of Medicine Report Details of New Studies and Findings in the Area of Pulmonary Fibrosis

Published in Blood Weekly, January 12th, 2012

2012 JAN 12 -- "Recent reports suggest that polymyxin B (PMX)-immobilized fiber may have beneficial effects in idiopathic pulmonary fibrosis (IPF) with acute exacerbation (AE). High mobility group box-1 (HMGB-1) is an important pro-inflammatory mediator that contributes to acute lung inflammation," scientists writing in the journal Blood Purification report.

"This study was aimed to investigate whether PMX treatment affects serum HMGB-1 levels and oxygenation in IPF patients with AE. Twenty IPF patients with AE were treated by PMX. PMX treatment was carried out once daily for 2 successive days. Serum HMGB-1 levels were measured before and after PMX...

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Source: Blood Weekly (2012-01-12)

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