Reports from College of Physicians & Surgeons Highlight Recent Research in Cysteine Endopeptidases

2012 JAN 19 -- Fresh data on Cysteine Endopeptidases are presented in the report "Intranasal delivery of caspase-9 inhibitor reduces caspase-6-dependent axon/neuron loss and improves neurological function after stroke." According to the authors of a study from New York City, New York, "Despite extensive research to develop an effective neuroprotective strategy for the treatment of ischemic stroke, therapeutic options remain limited. Although caspase-dependent death is thought to play a prominent role in neuronal injury, direct evidence of active initiator caspases in stroke and the functional relevance of this activity have not previously been shown."

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