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Ischemia

Researchers from Osaka University of Pharmaceutical Sciences Detail Findings in Ischemia

Published in Blood Weekly, January 26th, 2012

2012 JAN 26 -- Investigators publish new data in the report "Preventive effect of GGsTop, a novel and selective '-glutamyl transpeptidase inhibitor, on ischemia/reperfusion-induced renal injury in rats." According to the authors of recent research published in the The Journal of Pharmacology and Experimental Therapeutics, "GGsTop [2-amino-4-{[3-(carboxymethyl)phenyl](methyl)phosphono}butanoic acid], is a novel, highly selective, and irreversible '-glutamyl transpeptidase (GGT) inhibitor with no inhibitory activity on glutamine amidotransferases. In this study, we investigated the effects of treatment with GGsTop on ischemia/reperfusion-induced renal injury in...

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