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Stem Cell Research

Researchers from Harvard University Report on Findings in Stem Cell Research

Published in Blood Weekly, February 2nd, 2012

2012 FEB 2 -- "After acute kidney injury, mice with short telomeres develop increased damage with reduced proliferative capacity, which suggests an important role for telomere length in kidney repair. The enzyme telomerase reverse transcriptase (mTert) regulates telomere length; embryonic stem cells and certain adult stem cells express mTert, but whether cells in the adult kidney express mTert and whether these cells play a role in renal repair are unknown," scientists in Cambridge, Massachusetts report.

"Here, we found that telomerase protein and mRNA were highly enriched in renal papilla, a proposed niche of kidney stem cells. Using mTert-GFP reporter...

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