Serine Endopeptidases

New Serine Endopeptidases Research from Konkuk University Described

Published in Blood Weekly, February 2nd, 2012

2012 FEB 2 -- "In this study, we investigated whether the methanolic extract of yuzu (yuzu ME) and its components hesperidin and naringin, have anti-platelet activities. Yuzu ME and hesperidin inhibited collagen-, arachidonic acid (AA)-, ADP- and thrombin-induced rat platelet aggregation in vitro and ex vivo," scientists in Seoul, South Korea report.

"Naringin also inhibited platelet aggregation induced by collagen, AA, or thrombin, but not aggregation induced by ADP. The oral administration of yuzu ME or hesperidin prolonged mouse tail vein bleeding time in a dose-dependent manner in vivo," wrote H.Y. Yu and colleagues, Konkuk University.

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Source: Blood Weekly (2012-02-02)

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