Sepsis
Data on Sepsis Published by Researchers at University of Michigan School of Medicine
Published in Blood Weekly, February 16th, 2012
2012 FEB 16 -- Investigators publish new data in the report "Role of C3, C5 and anaphylatoxin receptors in acute lung injury and in sepsis." According to the authors of recent research from Ann Arbor, Michigan, "The complement system plays a major role in innate immune defenses against infectious agents, but exaggerated activation of complement can lead to severe tissue injury. Systemic (intravascular) activation of complement can, via C5a, lead to neutrophil (PMN) activation, sequestration and adhesion to the pulmonary capillary endothelium, resulting in damage and necrosis of vascular endothelial cells and acute lung injury (ALI)."
"Intrapulmonary...
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Source: Blood Weekly (2012-02-16)
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