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Sepsis

Scientists at Research Laboratory Describe Research in Sepsis

Published in Blood Weekly, February 16th, 2012

2012 FEB 16 -- New investigation results, "Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human blood," are detailed in a study published in Advances In Experimental Medicine and Biology. "Sepsis is a major world-wide medical problem with high morbidity and mortality," scientists in Bodo, Norway report.

"Gram-negative bacteria are among the most important pathogens of sepsis and their LPS content is regarded to be important for the systemic inflammatory reaction. The CD14/myeloid differentiation factor 2 (MD-2)/TLR4 complex plays a major role in the immune response to LPS," wrote D....

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