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Renal Disease

Research from University of Connecticut in Renal Disease Provides New Insights

Published in Blood Weekly, March 8th, 2012

2012 MAR 8 -- According to the authors of a study from Farmington, Connecticut, "Patients with renal failure and severe hyponatremia present a therapeutic dilemma."

"Conventional hemodialysis is necessary to correct blood chemistries and volume overload, yet it may raise serum sodium (Na) too quickly, potentially resulting in osmotic demyelination syndrome. We present the case of a patient who presented with renal failure requiring dialysis and also with a serum Na of 112 mEq/l," wrote E.M. Wendland and colleagues, University of Connecticut.

The researchers concluded: "Using a dialysate Na concentration of 130 mEq/l and by limiting the...

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