Virus Replication
Reports Summarize Virus Replication Research from Gifu University
Published in Blood Weekly, March 22nd, 2012
2012 MAR 22 -- Data detailed in "Functional characterization of EUL47 in productive replication, morphogenesis and infectivity of equine herpesvirus 1" have been presented. According to the authors of a study from Gifu, Japan, "EUL47 is a major component of the tegument of equine herpesvirus 1 (EHV-1). To determine its function, we used Red/ET cloning to delete its gene (gene 13) from EHV-1 strain Ab4p inserted into a bacterial artificial chromosome (BAC), yielding Ab4pattB'13."
"We also examined the reverted virus (Ab4pattB13R). Ab4pattB'13 replicated in rabbit kidney (RK)-13 cells, indicating that ORF13 is dispensable for virus replication in cell...
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Source: Blood Weekly (2012-03-22)
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