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Biotechnology

Researchers from Nara Institute of Science and Technology Report Details of New Studies and Findings in the Area of Biotechnology

Published in Blood Weekly, April 5th, 2012

2012 APR 5 -- A report, "The methyl-CpG-binding protein CIBZ suppresses myogenic differentiation by directly inhibiting myogenin expression," is newly published data in Cell Research. According to the authors of recent research from Takayama, Japan, "Postnatal growth and regeneration of skeletal muscle are carried out mainly by satellite cells, which, upon stimulation, begin to express myogenin (Myog), the critical determinant of myogenic differentiation. DNA methylation status has been associated with the expression of Myog, but the causative mechanism remains almost unknown."

"Here, we report that the level of CIBZ, a methyl-CpG-binding protein,...

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