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Ischemia

Studies in the Area of Ischemia Reported from University of Amsterdam

Published in Blood Weekly, April 26th, 2012

2012 APR 26 -- Investigators publish new data in the report "Mechanistic overview of reactive species-induced degradation of the endothelial glycocalyx during hepatic ischemia/reperfusion injury. 'Endothelial cells are covered by a delicate meshwork of glycoproteins known as the glycocalyx. Under normophysiological conditions the glycocalyx plays an active role in maintaining vascular homeostasis by deterring primary and secondary hemostasis and leukocyte adhesion and by regulating vascular permeability and tone," scientists in Amsterdam, Netherlands report.

"During (micro)vascular oxidative and nitrosative stress, which prevails in numerous metabolic...

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