Published in Blood Weekly, May 3rd, 2012
"We tested the hypothesis that DES-induced post-conditioning is mediated by BKCa upstream of the mitochondrial permeability transition pore (mPTP). Pentobarbital-anaesthetized male C57Black/6 mice were subjected to 45 min coronary artery occlusion (CAO) and 3 h reperfusion. Animals received either no intervention or dimethylsulphoxide (DMSO, 10 l g(1)). DES (1.0 MAC, 7.5 vol)...
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