Kidney Transplants
Investigators at University of Heidelberg Target Kidney Transplants
Published in Blood Weekly, May 3rd, 2012
2012 MAY 3 -- Investigators publish new data in the report "DR(high+)CD45RA(-)-Tregs Potentially Affect the Suppressive Activity of the Total Treg Pool in Renal Transplant Patients. 'Recent studies show that regulatory T cells (Tregs) play an essential role in tolerance induction after organ transplantation. In order to examine whether there are differences in the composition of the total CD4(+)CD127(low±)FoxP3(+)-Treg cell pool between stable transplant patients and patients with biopsy proven rejection (BPR), we compared the percentages and the functional activity of the different Treg cell subsets (DR(high+)CD45RA(-)-Tregs, DR(low+)CD45RA(-)-Tregs,...
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Source: Blood Weekly (2012-05-03)
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