Risk Factors

Each Pregnancy Increases Cancer Risk For BRCA1 and BRCA2 Carriers

Published in Breast Cancer Weekly, February 5th, 2000

Women carrying BRCA1 and BRCA2 germline mutations increase their chance of breast cancer with each pregnancy, researchers say.

H. Jernstrom and colleagues at the University of Toronto sought to find whether pregnancy increased the risk for development of hereditary breast cancer. Using a questionnaire in a matched case-control study, they gathered information from patients who carried BRCA1 or BRCA2 mutations and had developed breast cancer by the age of 40. They also gathered data from a control group of women who either were of the same age but did not have breast cancer or had been diagnosed with breast cancer after the age of 40.

Jernstrom et...

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Source: Breast Cancer Weekly (2000-02-05)

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