Cancer Therapies

High-Dose Chemotherapy for Breast Cancer Contraindicated

Published in Breast Cancer Weekly, April 8th, 2000

High-dose chemotherapy does not confer relapse-free or overall survival advantages to breast cancer patients, and, in fact, was associated with higher rates of death, according to a recent study.

The findings contrast with those of uncontrolled studies in patients with high-risk primary breast cancer treated with high-dose chemotherapy and autologous hematopoietic stem cell support, indicated researchers.

G.N. Hortobagyi, University of Texas M.D. Anderson Cancer Center, and colleagues conducted a prospective randomized trial comparing standard-dose chemotherapy with the same therapy followed by high-dose chemotherapy in patients who, after primary...

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Source: Breast Cancer Weekly (2000-04-08)

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