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Cancer Gene Therapy Week

Susan Hasty, Publisher

Table of Contents . . . July 4th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cancer Gene Therapy Week | Other Publications

Diagnostic Imaging - Functional and anatomic imaging quantifies gene transfer in murine tumors

Enzymology - Heat shock protein helps gene-directed enzyme prodrug therapy manage tumors

Gene Transfer - Fractalkine gene therapy relies on immune system support for tumor killing

Genetic Engineering - Gene-modified dendritic cells from cancer patients activate CTL clones

Vector Development -  Bifidobacterium infantis transmits suicide gene therapy to melanoma cells

Acute Lymphoblastic Leukemia - Multiple subclones identified in TEL-AML1 at diagnosis

Adrenocortical Tumors - Chromosome 17 mutations linked to adrenocortical tumors

Allergy and Immunology - Company introduces chemistry technology for oligonucleotide-based therapeutics

Arthritis - Risk of osteoarthritis associated with high production of interleukin

Bladder Cancer - Co-expression of RON and MET prognosticated transitional-cell carcinoma

Bone Marrow - Bone marrow lymphoid aggregates detected in malignant lymphomas

Oncology - Researchers provide details of new studies and findings in the area of oncology

Brain Cancer - DNA-dependent protein kinase blockade triggers autophagy in irradiated cells

Breast Cancer - Cell proliferation signature linked to extremely poor outcome in breast cancer

Breast Cancer - Reports advance knowledge in breast cancer research

Business & Finance - GlaxoSmithKline makes milestone payment, begins thrombocytopenia drug trial

Business Update - World's largest polymerase chain reaction manufacturing facility dedicated

Cancer Immunotherapy - Antigen-encoded viruses offer protection against prostate cancer

Vector Development - Researchers publish new studies and findings in the area of vector development

Cancer Immunotherapy - Reengineered dendritic cells need natural killer cells for melanoma targeting

Cancer Research - Research on apoptosis in cancer cell discussed

Cancer Therapy - Antitumor antibodies maintain therapeutic levels after gene transfer

Cancer Therapy - Endostatin gene therapy and gemcitabine join forces to battle lung cancer

Carcinogenesis - Allelic loss of DNA repair gene OGG1 against oxidative damage reported

Carcinogenesis - WNT-1 implicated in tumor differentiation in oral squamous cell carcinoma

Cardiology - Researchers provide details of new studies and findings in the area of cardiology

Collaborations - Reference lab, genetics technology provider expand molecular diagnostics group

Dermatology - Autologous vaccine powers immunological response to melanoma

Drug Delivery - Tumor cells take up tailor-made self-assembled polyelectrolyte shells

Drug Development - Introgen continues to advance INGN 007 for the treatment of cancer

Endocrinology - Findings in endocrinology provide new insights

Endocrinology - Gene therapies slay thyroid cancer cells in patients with end-stage disease

Endogenous Retrovirus - HERV rec interferes with germ cell development and may cause carcinoma

Enzymology - Researchers detail new studies and findings in the area of enzymology

Esophageal Cancer - Functional polymorphisms of SLC11A1 associated with risk of esophageal cancer

Finance - Cancer treatment-focused company retracts previously announced financing

Gastric Cancer - Loss of Ep-CAM (CO17-1A) expression predicts survival gastric cancer patients

Gene Research - Data from meeting of the American Society of Gene Therapy highlighted

Gene Silencing - Research add new data to gene silencing body of knowledge

Gene Transfer - Researchers' data advance gene transfer research

Hematology - Imatinib and mcl-1 antisense synergize to beat chronic myeloid leukemia

Hepatocellular Carcinoma - Murine liver tumors respond to combined suicide-cytokine gene therapy

Hodgkin Lymphoma - Receptor tyrosine kinases linked to classic Hodgkin lymphoma

Kidneys - Management of renal tumors in Birt-Hogg-Dube syndrome evaluated

Leukemia - HFE and TFR2 gene mutations analyzed in patients with acute leukemia

Leukemia - New variant t(6;15;17)(Q25;q22;q21) in acute promyelocytic leukemia discovered

Leukemia - Researchers provide details of new studies and findings in the area of leukemia

Leukemia - Variant t(8;10;21) found in patient with features mimicking atypical CML

Oncology - Agents targeting KIT exon 8 mutations may treat core-binding factor leukemia

Oncology - Antigene peptide nucleic acid cuts neuroblastoma growth via MYCN inhibition

Oncology - Research in oncology provides new insights

Orthopedics - Cytokine transfected tissue implants may avert aseptic loosening

Ovarian Cancer - Introgen's INGN 241 activates tumor selective cell death pathways

Paclitaxel - Apoptosis induced by 5-fluorouracil, cisplatin and paclitaxel in gastric cancer

Patents - European Patent Office grants patent allowance to protect anticancer drug

Personnel - Drug process development company appoints William Haseltine advisor to board

Product Licensing - DNA-focused biopharmaceutical company licenses 3 cancer vaccine targets to Merck

Prostate Cancer - Cancer cells transduced ex vivo stimulate antitumor immunity in mice

Prostate Cancer - Functional role of MIM implicated in prostate cancer cell biology

Prostate Cancer - Genetic changes noted in localized prostate cancer of Japanese patients

Proteomics - Researchers provide details of new studies and findings in the area of proteomics

Pulmonary Medicine - Findings advance knowledge in pulmonary medicine research

Vaccine Development - Introgen's INGN 241 effective against multiple cancers in preclinical studies

Vector Development - Calcium strengthens plasmid-lipid particle transfection

Vector Development - Findings in vector development provide new insights

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