Cancer Gene Therapy
Adenovirus-mediated antisense expression inhibits colorectal cancer cell growth
Published in Cancer Gene Therapy Week, April 17th, 2006
B. Zhang and colleagues, Shandong University, wrote that the study was done "to construct a recombinant adenovirus that can simultaneously express both antisense ODC and AdoMetDC and detect its inhibitory effect on the intracellular polyamine pool and colorectal cancer cell growth.
"A205-bp cDNA of AdoMetDC was reverse-inserted into recombinant pAdTrack-ODCas vectors and recombined with pAdEasy-1...
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