Published in Cancer Gene Therapy Week, November 6th, 2006
Study 1: According to a study from the United States, targeted therapy with a Salmonella typhimurium Leu-arginine auxotroph cures orthotopic human breast tumors in nude mice.
"We report here a modified auxotrophic strain of S. typhimurium that can target and cure breast tumors in orthotopic mouse models. We have previously reported development of a genetically modified strain of S. typhimurium, selected for prostate tumor targeting and therapy in vivo.
"The strain, termed S. typhimurium A1, selectively grew in...
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