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Cancer Gene Therapy

New cancer gene therapy study results from Center for Cancer Research described

Published in Cancer Gene Therapy Week, December 25th, 2006

Research findings, "Gene expression patterns distinguish colonoscopically isolated human aberrant crypt foci from normal colonic mucosa," are discussed in a new report. "Aberrant crypt foci (ACF) are considered the earliest identifiable preneoplastic colonic lesions; thus, a greater understanding of the nature of genetic changes underlying the transformation of normal colonic mucosa (NM) into ACF may provide insight into the mechanisms of carcinogenesis. ACF were identified by indigo carmine spraying onto colonic mucosa during colonoscopy and isolated as standard pinch biopsies of the mucosal areas containing the ACF," investigators in the United States report.

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