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Cancer Gene Therapy

Scientists at Lanzhou University, Institute of Urology release new data on cancer gene therapy

Published in Cancer Gene Therapy Week, April 6th, 2009

A report, 'Construction of urothelium-specific recombinant adenovirus and its inhibition in bladder cancer cell,' is newly published data in Urologia Internationalis. In this recent report, researchers in Lanzhou, People's Republic of China conducted a study "To construct urothelium-specific recombinant adenovirus and investigate its inhibition in bladder cancer cell. RT-PCR analysis was used to determine expression patterns of hUPII and coxsackie adenovirus receptor on multiple cell lines."

"Transient transfection and luciferase detecting assay were used to detect tissue specificity of the hUPII promoter. Recombinant adenovirus Ad-UPII-E1A and Ad-UPII-Null were...

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