Apoptosis

Chinese University of Hong Kong, Department of Surgery Details Research in Apoptosis

Published in Cancer Gene Therapy Week, March 14th, 2011

2011 MAR 14 -- Research findings, 'ZBP-89 enhances Bak expression and causes apoptosis in hepatocellular carcinoma cells,' are discussed in a new report. "ZBP-89 can enhance tumor cells to death stimuli. However, the molecular mechanism leading to the inhibitory effect of ZBP-89 is unknown," scientists writing in the journal Biochimica Et Biophysica Acta report.

"In this study, 4 liver cell lines were used to screen for the target of ZBP-89 on cell death pathway. The identified Bak was further analyzed for its role in ZBP-89-mediated apoptosis. The result showed that ZBP-89 significantly and time-dependently induced apoptosis. It significantly...

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Source: Cancer Gene Therapy Week (2011-03-14)

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