Indiana University
Nephroblastomas can arise from germ cell tumor origins
Published in Cancer Law Weekly, July 10th, 2004
According to researchers in the United States, "we report a nephroblastoma arising in a germ cell tumor of testicular origin occurring in a 22-year-old man. Orchiectomy demonstrated a malignant mixed germ cell tumor composed of mature and immature teratoma with nephroblastoma and rhabdomyosarcoma. Following chemotherapy, the patient developed supraclavicular and retroperitoneal lymphadenopathy."
"Excision demonstrated metastatic teratoma at both sites. No recurrence was noted with 21 months of additional follow-up. Using tissue microdissection and loss of heterozygosity analysis, we investigated...
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Source: Cancer Law Weekly (2004-07-10)
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