Apoptosis

Apoptosis genes regulated by Wnt/beta-catenin pathway identified

Published in Cancer Law Weekly, November 18th, 2006

A study from the People's Republic of China has reported on the identification of genes regulated by Wnt/beta-catenin pathway and involved in apoptosis via microarray analysis.

"Wnt/beta-catenin pathway has critical roles in development and oncogenesis. Although significant progress has been made in understanding the downstream signaling cascade of this pathway, little is known regarding Wnt/beta-catenin pathway modification of the cellular apoptosis.

"To identify potential genes regulated by Wnt/beta-catenin pathway and involved in apoptosis, we used a stably integrated, inducible RNA interference (RNAi) vector to specific inhibit the expression and...

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Source: Cancer Law Weekly (2006-11-18)

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