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New life sciences study findings have been reported from University of Toronto

Published in Cancer Law Weekly, August 23rd, 2008

Investigators publish new data in the report 'Major role of human KLK14 in seminal clot liquefaction.' "Liquefaction of human semen involves proteolytic degradation of the seminal coagulum and release of motile spermatozoa. Several members of human kallikrein-related peptidases (KLKs) have been implicated in semen liquefaction, functioning through highly regulated proteolytic cascades," researchers in Toronto, Canada report.

"Among these, KLK3 (also known as prostate-specific antigen) is the main executor enzyme responsible for processing of the primary components of semen coagulum, semenogelins I and II. We have recently identified KLK14 as a potential activator of...

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