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Pathology and Oncology

Researchers from University of Heidelberg describe findings in pathology and oncology

Published in Cancer Law Weekly, August 23rd, 2008

According to a study from Heidelberg, Germany, "Supported by different investigations, multi-step models for tumorigenesis have been proposed for epithelial tumors. The age specific incidence of some cancers shows an exponential rise with increasing patient age."

"Yet, the onset and the slope of incidence curves varies between tumor types. One simple explanation for this disparity is that the number of mutations required for transformation differs in various tissues. We used a homogeneous Poisson process to estimate the number of events (N) and the intensity or event rate (1) that might be needed for cancer development in various tissues (colon, prostate, oralpharynx,...

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