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Cancer Gene Therapy

Researchers from Nagoya University detail findings in cancer gene therapy

Published in Cancer Law Weekly, September 6th, 2008

A new study, 'Non-engineered, naturally oncolytic herpes simplex virus HSV1 HF-10: applications for cancer gene therapy,' is now available. According to a study from Nagoya, Japan, "Oncolytic HSV-1 has been developed as a novel anticancer agent. According to the properties and functions of HSV-1 encoded proteins, several genes have been targeted for engineering of oncolytic HSV-1."

"As a result, a variety of strategies have been applied to the engineering of oncolytic HSV-1. Success in cancer therapy for solid tumors requires a maximal oncolytic effect; however, recombinant HSV-1 that has been adapted to meet neurotoxicity requirements for the treatment of brain tumors...

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