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Cancer Gene Therapy

Data on cancer gene therapy discussed by investigators at University of Birmingham, Institute for Biomedical Research

Published in Cancer Law Weekly, September 26th, 2009

A report, 'Induction of thrombospondin-1 partially mediates the anti-angiogenic activity of dexrazoxane,' is newly published data in British Journal of Cancer. According to a study from Edgbaston, the United Kingdom, "Considerable interest lies in the identification of novel anti-angiogenic compounds for cancer therapy. We have investigated whether dexrazoxane has anti-angiogenic properties and if so, the mechanism of the inhibition."

"The phenotypic effects of dexrazoxane on endothelial cell behaviour was investigated both in vitro using human umbilical vein endothelial cells (HUVECs) in cell proliferation, migration, cell cycle and aortic ring assays; and in...

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