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Bladder Cancer Genetics

Findings from University of Texas, M. D. Anderson Cancer Center in bladder cancer genetics reported

Published in Cancer Law Weekly, January 9th, 2010

Scientists discuss in 'Genetic variations in PI3K-AKT-mTOR pathway and bladder cancer risk' new findings in bladder cancer. According to a study from the United States, "Genetic variations in phosphoinositide-3 kinase (PI3K)-AKT-mammalian target of rapamycin (mTOR) pathway may affect critical cellular functions and increase an individual's cancer risk. We systematically evaluate 231 single-nucleotide polymorphisms (SNPs) in 19 genes in the PI3K-AKT-mTOR signaling pathway as predictors of bladder cancer risk."

"In individual SNP analysis, four SNPs in regulatory associated protein of mTOR (RAPTOR) remained significant after correcting for multiple testing: rs11653499...

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