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Cancer Vaccine Week

Susan Hasty, Publisher

Table of Contents . . . June 30th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cancer Vaccine Week | Other Publications

Cancer Vaccine - Antitumor immunity induced by electrofusion of tumor and dendritic cells

Cancer Vaccine - Apoptosis plus CD80 costimulation promote immune response by melanoma cells

Cancer Immunotherapy - Vaccine based on high-affinity receptor suppresses tumor angiogenesis

Glioma - Monocytes kill brain tumor cells expressing macrophage colony-stimulating factor

Lymphoma - Myc does not require E2f1 to induce Arf, p53, or apoptosis in B cells

Pancreatic Cancer Vaccine - MnSOD expression after pancreatic cancer vaccination may be suppressive

Adrenal Cancer - The adrenal cortex is controlled by fragments from the same mother peptide

Apoptosis - Caspase inhibition switches doxorubicin-induced apoptosis to senescence

Apoptosis - ErPC triggers apoptosis via Bcl-2-dependent mitochondrial pathway

Brain Tumors - TMEFF1 may behave as a tumor suppressor gene in brain cancers

Breast Cancer - Antioxidants and vitamins may reduce estrogen-associated breast cancer risk

Breast Cancer - Careful standardization needed for multicenter breast cancer genetic screening

Breast Cancer - Increased expression of the Bfl-1 gene may contribute to breast cancer

Cancer Therapy - Engineered adenoviruses selectively destroys tumor cells

Cell Death - Distinct mechanisms exist for proapoptotic effects of cPG in endothelial cells

Childhood Cancer - Fetal mouse genetic and epigenetic mechanisms modulated by cigarette smoke

Choriocarcinoma Cell Line - The uptake of H-3-5HT by JAR cells occurs exclusively through SERT

Colon Cancer - Methylation-induced G2 /M arrest requires a full complement of hMLH1

Colorectal Carcinoma - FADD interacts with methyl-CpG binding domain protein

Drug Design - Therapeutic antibodies for targeted treatment of cancer are the next generation

Drug Manufacturing - New manufacturing contract announced

Familial Cancer - Genomic rearrangements account for more than one-third of the BRCA1 mutations

Gallbladder Cancer - Tumor suppressor expression patterns differentiate two gallbladder carcinoma types

Human Ectocervical Cells - HEC carcinogenesis results in resistance to 5-fluorouracil-induced apoptosis

Human Genotyping - Researchers propose an international effort to create phenomic databases

Human Malignancy - Development of malignant tumors has been linked to reactivation of telomerase

Intravascular Coagulation - Tissue factor messenger RNA is higher in cancer and hypercoagulable diseases

Leukemia - LAF4, AF5q31 may define family involved in pathogenesis of 11q23-associated ALL

Leukemia - Proteasome inhibitors and other chemotherapeutic agents alter Bax conformation

Leukemia - Treatment-specific changes in gene expression discriminate in vivo drug response

Melanoma - Mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia

Melatonin - The effect of melatonin as a geroprotector in mice is dose dependent

Metastatic Breast Cancer - Circulating tumor cells in peripheral blood predict poor survival

Multiple Myeloma - Initial clinical data reported from phase I/II trial of GVAX vaccine

Mutagenesis - Non-homologous end joining is important in cell cycle-arrested cells

Osteosarcoma - HGF activates both the mitogen and motogen machinery in osteosarcoma cells

Ovarian Cancer - The FANC-BRCA pathway is disrupted in a subset of ovarian tumor lines

Pancreatic Neoplasms - Recent discoveries in gene expression in neoplasms of the pancreas are presented

Prostate Cancer - (dARA55) coregulator inhibits AR transcriptional activity in prostate cancer

Prostate Cancer - Prostate DNA undergoes structural changes with increasing age

Proteomics - Gam1 activates E4-dependent transcription possibly by inactivating HDAC1

Proteomics - HIPK1 may play a role in tumorigenesis, perhaps by regulating p53, Mdm2, or both

Proteomics - PDZ-M1-induced apoptosis was not observed when c-myc null fibroblasts used

Pulmonary Carcinogen - NNK and tobacco-specific nitrosamines are involved in carcinogenesis

Therapeutic Vaccines - Patent granted for herpes vaccine; peptide may be used as adjuvant for vaccines

Thyroid Cancer - PTTG and FGF-2 expression are potential prognostic markers for thyroid cancer

Tumor Mutation - Mutations in mismatch repair genes can lead to microsatellite instability

Tumor Suppression - Nuclear localization of Y-box factor YB1 requires wild-type p53

mtDNA Mutation - p53 does not affect mtDNA mutation or mitochondrial ultrastructure

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