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Cancer Vaccine Week

Susan Hasty, Publisher

Table of Contents . . . December 29th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cancer Vaccine Week | Other Publications

Anticancer Therapy - The mevalonate synthesis pathway is a potential therapeutic target in cancer

Breast Cancer - Advexin vaccine therapy to begin phase I/II

Bladder Cancer - CD40 ligand immunogene therapy protects against bladder malignancies

Immunology - Transfected tumor cells boost antitumor responses in lung cancer patients

Anticancer Drug Clearance - Tumor-up-regulated cytochrome P4501B1 enzyme can be targeted by cytotoxic T cells

Antioxidants - Strawberry extract alters proliferation of HepG2 human liver cancer in vivo

Biliary Tract Cancer - Low-dose Imantinib with 5-FU holds potential for biliary tract cancers

Biliary Tract Carcer - NSAIDs may help prevent pancreaticobiliary maljunction carcinogenesis

Biological Therapy - The Th1/Tc1 circuit can produce tumor-specific CTL, even though Th2 can kill

Breast Cancer - A decreased level of ERbeta mRNA may be associated with breast tumorigenesis

Breast Cancer - Aromatase inhibitors' signal disruption mechanism differs from Tamoxifen

Breast Cancer - Combination genomics technique greatly improves breast carcinoma detection

Breast Cancer - Drug-induced apoptosis mechanism via DR-dependent pathway not fully understood

Breast Cancer - Expression of transglutaminases displayed in human breast cancer

Breast Cancer - Herstatin inhibits heregulin-mediated breast cancer cell growth

Breast and Prostate Cancer - Telomere stability correlates with longevity after exposure to radiation

Colon Cancer - CD44v6 expression may be a clinically useful indicator of colon cancer

Colon Cancer - CDX2 inactivation in colon cancer results from defects in trans-acting pathways

Colon Cancer - In vitro chemosensitivity analysis of human colon tumor cell lines shows promise

Colon Cancer - p53 gene mutations are rare in human papillomavirus-associated colon cancer

Colon Carcinoma - Detection of differentially expressed HES-6 gene in metastatic colon carcinoma

Ewing Sarcoma - Pamidronate inhibits Ewing sarcoma cell growth in vitro

Hepatocellular Carcinoma - More studies needed to reveal COX2 inhibitors affect on liver disease

Leukemia - AT islands in fragile sites can function as matrix attachment regions

Leukemia - PTEN expression in leukemic T cells leads to reduced proliferation

Lung Cancer - DNA analysis may help refine sputum exams, improve early lung cancer detection

Lung Cancer - Parathyroid hormone-related protein could promote cancer progression in vivo

Lung Cancer - Researchers establish patient-like SCID mouse model

MALT Lymphoma - Stability and subcellular localization of API2-MALT1 chimeric protein

Melanoma - Intracellular regulation of evodiamine-induced A375-S2 cell death

Multiple Myeloma - Alterations of RAS signaling are critical in multiple myeloma pathogenesis

Multiple Myeloma - High-dose chemotherapy more beneficial for MM patients with high-risk features

Multiple Myeloma - MM antigen HM1.24 loaded in adeno-associated virus produces anticancer T cells

Myeloid Tumors - Mutational analysis of ST7 do not commonly contribute to human myeloid tumors

Oncogene Activation - Poleta is important in inducing hypermutability in codon 12

Ovarian Cancer - Autoantibody to epithelial cell adhesion molecule is higher in ovarian cancer

Papillary Thyroid Carcinoma - BRAF mutations are restricted to papillary carcinomas

Pediatric Cancer - Researchers investigate alteration of the Axin gene in pediatric neoplasms

Pituitary Tumors - A pituitary-derived MEG3 isoform functions as a growth suppressor in tumor cells

Prostate Cancer - GSTP1 QMSP improves sensitivity of histologic review of random needle biopsies

Prostate Cancer - NFkappaB is a pivotal transcription factor in prostate cancer metastasis to bone

Renal Cell Carcinoma - Epidermal growth factor receptor blockade may supplement cytotoxic chemotherapy

Tissue Analysis - MALDI-MS allows direct analysis of drug candidates in tissue

Tumor Inhibition - A gap junction-independent tumor-suppressing effect of connexin 43 reported

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