Tumor Growth

Amine oxidases and tumors are correlated

Published in Cancer Vaccine Week, March 8th, 2004

Both oxidant and antioxidant enzymes are involved in carcinogenesis, researchers say.

"The physiological function in living organisms of amine oxidases (AO) is not completely established but is certainly related to the biogenic amines metabolism and, therefore, involved in essential processes such as the cell growth and differentiation," investigators in Italy report.

"A correlation between degree of tumor malignancy and level of AO activity has been reported. The catalytic products of oxidative deamination of amines (hydrogen peroxide and aminoaldehyde) exert a cytotoxic effect and are considered cell growth inhibitors," wrote P. Pietrangeli and...

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Source: Cancer Vaccine Week (2004-03-08)

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