Cancer Vaccine

Expression of the cell surface mucin gene family in adenocarcinomas reported

Published in Cancer Vaccine Week, December 6th, 2004

Scientists report the expression of the cell surface mucin gene family in adenocarcinomas in a recent issue of the International Journal of Oncology.

According to recent research from Australia, "Cell surface mucins are complex glycoproteins expressed on the apical membrane surface of mucosal epithelial cells. In malignant epithelial cells they are thought to influence cell adhesion, and are clinical targets for tumor immunotherapy and serum tumor marker assays. We have compared expression of MUC1, MUC3, MUC4, MUC11, MUC12, and MUC13 mRNA in epithelial cancers and/or cell lines with non-malignant tissues. In non-malignant tissues, MUC3, 4, 11, 12 and 13 were...

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Source: Cancer Vaccine Week (2004-12-06)

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