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Cancer Vaccine Week

Susan Hasty, Publisher

Table of Contents . . . May 30th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cancer Vaccine Week | Other Publications

Cancer Vaccines - Cancer immunotherapy targets minor histocompatibility antigens

Cancer Vaccines - Dendritic-cell-based therapeutic vaccination against cancer reviewed

Cancer Vaccines - Migration of dendritic-cell-based cancer vaccines reviewed

Cancer Vaccines - Role of CD4+ cells and antibodies in breast cancer protection described

Cancer Vaccines - Support for immunological mechanism of cancer vaccines research published

Acute Myeloid Leukemia - RT-PCR is an early predictive factor of relapse risk in AML with t(8; 21)

Adenocarcinoma - Secondhand smoke induces adenocarcinoma via p16//DAPK/RASSFIA gene inactivation

Adrenocortical Carcinoma - HLA-DRB1* 01 genotype increases risk for adrenocortical carcinoma

Adverse Drug Reaction - FDA to change regulations regarding side-effect information in drug ads

Apoptosis - Citrus limonoids induced apoptosis in human neuroblastoma cells

Apoptosis - NF-kappa B overrides apoptotic program of TNFr 1 but not CD40 in carcinoma cells

Cancer Therapy - Researchers' findings advance cancer therapy research

Barrett Esophagus - limitations of therapies for dysplasia in Barrett esophagus presented

Bioinformatics - Computer-aided image analysis quantifies tumor vascularity

Bladder Cancer - Multiple mechanisms downregulate CDKN1C in bladder cancer

Brain Cancer - Hypoxia drives glioma growth through signals that elicit angiogenesis

Breast Cancer - AMAP1 expression provides targets to inhibit breast cancer invasive activities

Breast Cancer - Aberrant HOX gene expression related to breast cancer development

Cancer Therapy - Studies describe new findings in cancer therapy research

Breast Cancer - ERBB2 variant Ile654Val associated with increased familial breast cancer risk

Breast Cancer - HIV Tat targeted into mitochondria of breast cancer cells

Breast Cancer - Imatinib mesylate monotherapy used to treat metastatic breast cancer

Breast Cancer - Mammaglobin A is a promising marker for breast cancer

Breast Cancer - Melatonin-estrogen interactions related to breast cancer

Breast Cancer - P16 and its cytoplasmic sequestration is a feature of breast carcinoma

Cancer Vaccines - New research in the area of cancer vaccines detailed

Breast Cancer - RAD21 supression decreases cell growth in breast cancer cells

Breast Cancer - SPARC sways survival and tumor progression in breast cancer patients

Breast Cancer - The phyotochemical derivative DIM diminishes angiogenesis in breast tumors

Breast Cancer - Valproic acid/RA/Aza-dC restores silenced RAR beta 2 expression in breast cancer

Breast Cancer Screening - Links between mammography access and breast cancer stage reported

Breast Cancer Therapy - Accuracy of 192Ir HDR breast brachytherapy dosimetry planning determined

Gastroenterology - Researchers publish new studies and findings in the area of gastroenterology

Business & Finance - Melanoma-focused pharmaceutical company reports Q1 2005 financial results

Business Update - Developer of biological products issues correction for computational error

Cancer Drugs - Manumycin A-induced apoptosis enhanced by methoxyamine in myeloid leukemia cells

Cancer Immunotherapy - Complete immune depletion and stem cell transplantation stops cancer metastasis

Cancer Immunotherapy - Genetically modified lymphocytes recognize and kill human tumor cells

Cancer Immunotherapy - Treatment combining interleukin-2 and radiotherapy treats scalp angiosarcoma

Oncology - New findings in the area of oncology detailed

Cancer Therapy - Antineoplastic potential of TNF discussed

Cancer Therapy - Continual progress in cancer research yields promising cancer therapies

Cancer Therapy - Copolymers synthesized as potential anticancer conjugates

Cancer Therapy - Depsipeptide makes cancer cells more vulnerable to TRAIL gene therapy

Cancer Therapy - Dual gene-virotherapy eradicates established tumors in animal models

Cancer Therapy - Hormonal traits predict how well prostate cancer will respond to therapy

Oncology - Recent findings illuminate research in oncology

Cancer Therapy - Integrated approach identifies genes that determine cancer cell chemosensitivity

Cancer Therapy - Reduced tumor interstitial pressure encourages chemotherapy dissemination

Cancer Therapy - Researchers' data advance cancer therapy research

Cancer Therapy - Skin cancer treatments focus on surgical approaches, new noninvasive therapies

Oncology - Recent findings in oncology provide new insights

Cancer Therapy - Synergistic antitumor activity reported for GVAX cancer vaccine

Cancer Vaccines - Native blood dendritic cells possess tumoricidal potential

Cancer Vaccines - New findings in the area of cancer vaccines detailed

Cancer Vaccines - Programming hematopoietic stem cells provides long-term T cell immunity

Cancer Vaccines - Tumor proteome suppressed by an adenovirus-based skin patch vaccine

Oncology - Research in oncology provides new insights

Cell Biology - Endothelial cell counter-receptor fosters CD97-induced angiogenesis

Chlamydial Infections - Genome sequencing for Chlamydophila abortus may help curb infections

Chronic Myeloid Leukemia - p21(WAF)induction by 5-Aza-CdR leads to p53-independent apoptosis in CML

Colon Cancer - IL-8 promotes cell proliferation in human colon carcinoma cells

Colon Cancer - Invasive colorectal cancers have classic gene expression profiles

Colon Cancer - Subpopulation of T84 human colon cancer cells characterized

Oncology - Researchers report details of new studies and findings in the area of oncology

Colorectal Adenoma - PPARgamma Pro12Ala polymorphism may help protect against colorectal adenoma

Colorectal Cancer - Digital fecal occult blood test not suitable as primary screening test

Colorectal Cancer - OcculTech fecal occult blood test suitable for colorectal neoplasia screening

Diabetes Complications - Diabetic mastopathy can mimic cancer in women with type 2 diabetes

Diagnostics - Candidate proteins differentiate hepatitis B-related liver cancer

Diagnostics Imaging - Recent findings in diagnostics imaging described

Virology - Recent studies add new data to virology research

Drug Delivery - Cisplatin/adriamycin release from hydrogel has synergistic antitumor effects

Drug Development - IND submitted to U.S. FDA for trial of malignant melanoma therapy

Endocrinology - Parathyroid adenomas present unique gene expression profiles

Endocrinology - Reports describe recent advances in endocrinology research

Enzymology - Heparanase gene inhibition crushes melanoma cell invasion mechanisms

Enzymology - New findings in the area of enzymology detailed

Epstein-Barr Virus - EBI3 may have role in regulating antiviral or antitumoral immune response

Finance - Biopharma reports Q1 net loss of $9.7 million

Finance - Biotech company focused on infectious disease, cancer reports Q1 2005 results

Finance - Biotechnology company reports first quarter 2005 financial results

Gastric Cancer -  H. pylori+enhanced mucosal IL-1beta production increases gastric cancer risk

Gastric Cancer - Bcl-2 gene activation implicated in aspirin-induced apoptosis in gastric cancer

Gastric Cancer - IL-8/IL-10/TNF-alpha polymorphisms associated with increased gastric cancer risk

Gastroenterology - Cases of early-stage carcinoids of the gastrointestinal tract analyzed

Gastroenterology - Gastrointestinal stromal tumor treated with imatinib

Gastroenterology - Researchers provide details of new studies and findings in the area of gastroenterology

Gene Expression - Octamer/Sox elements required for cis regulation of Nanog gene expression

Gene Research - Genetic polymorphisms modify breast cancer susceptibility in Korean women

Gene Transfer - Dominant-negative Epstein-Barr virus nuclear antigen 1 impairs cancer growth

Gene Transfer - SIRES bicistronic vectors enable clinicians to monitor therapeutic genes

Gynecology - The CD109 gene is overexpressed in uterine cervix squamous cell carcinoma

HIV/AIDS Research - New pharmacokinetic data on taking Lexiva with Nexium released

Head & Neck Cancer - Hypoxia inducible factor levels correlate with esophageal cancer metastasis

Healthcare Coverage - Insurance company introduces health portfolio

Hematology - Cyclin B1 predicts favorable outcomes in patients with follicular lymphoma

Hematology - Rapamycin suppresses VEGF and harnesses chronic myeloid leukemia growth

Human Papillomavirus - High-risk mucosal HPV infections during infancy and childhood reviewed

Human Papillomavirus - Immune control of HPV-associated anogenital disease reviewed

Human Papillomavirus - Molecular diagnosis of human papillomavirus infections reviewed

Kidney Cancer - Retroperitoneoscopic tumor ablation via ultrathin cryoprobes effective

Laryngeal Cancer - Helicoidal axial CT useful in staging anterior vocal commissure tumors

Lung Cancer - Angiogenesis biomarkers forecast non-small-cell lung cancer aggression

Lung Cancer - Expression of TARSH gene in MEFs senescence implicated in human lung cancer

Lung Cancer - Fatty acid ratios manipulate cancer cell invasion through genetic regulation

Lung Cancer - P73 dinucleotide polymorphism associated with a reduced lung cancer risk

Melanoma Vaccine - Stat3 activity in melanoma cells affects NO-mediated antitumor effects

Mergers & Acquisitions - Cancer product development company completes acquisition of DELEX

Mergers & Acquisitions - GlaxoSmithKline announces acquisition

Monoclonal Antibodies - Number of BAT/CD3 cells appear to vary by cancer type

Natural Products -  Shiraia bambusicola derivative is a potent angiogenesis inhibitor

Natural Products - Enzymatic pathways are conduits for apigenin-mediated antiangiogenesis

Neurofibromatosis - NF2 gene mutation detected in 100% of inherited cases via multiple techniques

Oncology - Cimetidine impairs angiogenesis to curtail tumor growth

Oncology - Delta Np73 antisense activates apoptosis in neuroblastoma cells

Oncology - Ellagic acid selects angiogenic cytokine receptors for inhibition

Oncology - Factors raise cancer risk in those with current and past HBV infections

Oncology - Fine-needle aspiration biopsy tumor samples suitable for microarray analysis

Oncology - Hepatitis B virus-related inflammation propagates mitochondrial loop mutations

Oncology - New findings in oncology described

Oncology - Oncolytic adenovirus-based antiangiogenic gene therapy attacks growing tumors

Oncology - Proteins that control angiogenesis increase before the advent of liver cancer

Ovarian Cancer - Increase in antibodies to MUC1 associated with reduced cancer risk

Pediatric Oncology - Antisense bcl-2 launches compensatory activity in neuroblastoma cells

Pediatric Oncology - Central venous catheter-related complications characterized

Personnel - Zbigniew Wlwszek, PhD, appointed chief scientific officer of biotech company

Prostate Cancer - Pharmacokinetics of isotope-labeled antibody specific for PSA reported

Prostate Cancer - Secondary ellagic acid therapy in HRPC patients on standard chemotherapy tested

Proteomics - Hepatitis B virus X protein and hepsin interact to alter liver cell activity

Pulmonary Medicine - Amino acids make aerosolized gene delivery more robust

Pulmonary Medicine - PEI-plasmid DNA complexes stimulate minimal proinflammatory response

Pyothorax-Associated Lymphoma - ATM and ATR gene mutations have a role in pyothorax-associated lymphoma

Quality Assurance - New consensus ambulatory performance measures established by collaborative group

Retroviral Vectors - Chemotherapy augments gene therapy targeting tumor vessels

Shingles - Pharmaceutical co. submits biologics license application for shingles vaccine

Skin Cancer - Low-dose retinoids prevented cutaneous SCC in organ transplant recipients

Soft Tissue Sarcoma - RASSF1A inactivation is a common event in soft tissue sarcomas

Supratentorial Glioblastoma - Temozolomide and cis-retinoic acid with radiation evaluated in phase II study

Telomerase - Telomerase inhibition via ribozyme targeting hTR inhibits breast cancer

Thyroid Cancer - Novel genes identified in thyroid oncocytic adenomas

Tumor Suppression - AP-1 dimers regulated transcription of p14/p19(ARF) tumor suppressor gene

Tumor Suppression - Cross-regulation between RUNX family members controls RUNX protein expression

Tumorigenesis - DNA damage response used as anti-cancer barrier in early human tumorigenesis

Tumorigenesis - Hematopoietic cells regulate angiogenic switch during tumorigenesis

Vector Development - Researchers publish new studies and findings in the area of vector development

Virology - New findings in the area of virology described

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